Why Was The Women's Health Initiative Stopped Early?
According to a press release, the DSMB halted the HT WHI study principally because the risk for invasive breast cancer had become significantly higher in the HT group compared with the placebo group.
How has the use of menopausal hormone therapy changed since the women's Health Initiative study?
Instead, the Women's Health Initiative study found that taking estrogen plus progestin hormone replacement therapy — HRT — actually increased a woman's risk of heart disease and breast cancer. The study had a huge effect: Within months the number of women using HRT dropped by almost half.
The Last Word On Hormone Therapy From the Women's ...
What were the results of the women's Health Initiative concerning hormone therapy?
WHI results in 2002 found that post-menopausal women taking combination (estrogen and progestin) hormone therapy for menopause symptoms had an increased risk for breast cancer, heart disease, stroke, blood clots, and urinary incontinence.
Largest women's health prevention study ever – Women's Health Initiative
Women's Health Initiative (WHI)
Women's Health Initiative (WHI) - Full Text View - ClinicalTrials ...
Why was the WHI study terminated early?
One treatment-arm of the Women's Health Initiative (WHI) study was recently terminated because the overall risks of hormone treatment were considered to outweigh the benefits. The main findings were an increased risk of venous thromboembolism and a decreased risk of osteoporotic fractures with treatment.
[After the early termination of the Women's Health Initiative study ...